DE MEEUS Thierry's profile
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DE MEEUS Thierry

  • Intertryp, IRD, Cirad, Univ Montpellier, Montpellier, France., IRD, Montpellier, France
  • Biodiversity, Dispersal & Migration, Evolutionary ecology, Habitat selection, Host-parasite interactions, Microbial ecology & microbiology, Molecular ecology, Mycology, Parasitology
  • recommender

Recommendations:  0

Review:  1

Areas of expertise
Degrees 21/01/1999: Post-PhD (Habilitation à Diriger des Recherches) at Montpellier II University. 27/06/1991: PhD of Physiology and Population and Organismal Biology at Montpellier II University. September 1989: Pre PhD of Sciences of Evolution and Ecology at Montpellier II University. September 1988: Pre-PhD of Parasitology: Ecology, Pathology at Montpellier II University. October 1987: Probation in experimental parasitology at Montpellier II University. June 1985: Masters in Population and organismal biology at P. and M. Curie University (Paris 6). Appointed positions 01/08/2015-Present: Full time senior researcher (DR1) in the IRD in the team Interactions hôtes - vecteurs - parasites dans les infections par des trypanosomatidae - (INTERTRYP), UMR177 IRD/CIRAD, , TA A-17/G, Campus International de Baillarguet, 34398 Montpellier Cedex 5, France. 01/09/2012-31/07/2015: Full time senior researcher (DR1) in the IRD in the team Interactions hôtes - vecteurs - parasites dans les infections par des trypanosomatidae - (INTERTRYP), UMR177 IRD/CIRAD and posted at the Centre International de Recherche-Développement sur l'Elevage en zone Subhumide (CIRDES), 01 BP 454, Bobo-Dioulasso 01, Burkina-Faso. 05/01/2012-01/09/2012: Full time senior researcher (DR2) in the IRD in the team Interactions hôtes - vecteurs - parasites dans les infections par des trypanosomatidae - (INTERTRYP), UMR177 IRD/CIRAD, France. 02/03/2009-04/01/2012: Full time senior researcher (DR2) in the CNRS given available to the IRD and posted at UMR 177 IRD/CIRAD, CIRDES, 01 BP 454 Bobo-Dioulasso 01, Burkina-Faso. 01/10/2005-01/03/2009: Full time senior researcher in the CNRS in the Laboratory 'Génétique et Evolution des Maladies Infectieuses', UMR 2724 CNRS/IRD Montpellier. 01/01/2004-30/09/2005: Full time and permanent researcher in the CNRS in the Laboratory 'Génétique et Evolution des Maladies Infectieuses', UMR 2724 CNRS/IRD Montpellier. 01/11/1998-31/12/2003: Full time and permanent researcher in the CNRS in the 'Centre d'Etude sur le Polymorphisme des Microorganismes', UMR 9926 CNRS/IRD Montpellier. 01/10/1993-31/10/1998: Full time and permanent researcher in the CNRS in the Laboratory 'Biologie des Populations d'Helminthes Parasites', UMR 5555 CNRS/Université Montpellier II 01/10/1992-31/09/1993: Temporary lecturer of population genetics in Montpellier II University. 01/10/1991-31/03/1992: Six month grant from the British Council at the School of Biological Sciences, University of Wales, Bangor, Gwynedd, LL57 2UW, UK. 01/10/1985-30/09/1986: Military service at Spire (Germany). Research experience During my PhD, I have studied the mechanisms of maintenance of adaptive polymorphism and evolution of habitat preference. I have used field studies, experimental tests and theoretical (analytical and computer simulations) modelling. The biological model consisted in two species of ecto-parasitic copepods and their three hosts (in the Mediterranean), turbot, brill and flounder. The fact that these organisms are marine, naturally involved me into marine biology topics. I also had to develop skills in programming (in Pascal) and in isoenzymatic genotyping. During my Post-doc in Bangor, I was trained to theoretical population genetics of structured population, in particular as regard to parameter estimation and testing of Wright's F-statistics. When coming back to Montpellier I kept studying adaptive polymorphism and habitat preference but more and more got involved in population genetic structure of hosts and their parasites. I got involved in studies on host-manipulating parasites as well. I have studied different kind of organisms as parasitic copepods, cestodes, trematodes, fungi, bacteriae, trypanosomes, leishmania, ticks, tsetse flies, gammarid amphipods, marine and fresh water snails, mussels, rats and deer. Presently my main areas of investigation concern host and parasite co-structures and the use of molecular markers in ecological inferences, and in particular in epidemiological inferences; and the theoretical and applied population genetics of clonal organisms. The main programs I am currently supervising or undertaking are: Population genetics of trypansosomes and their vectors in Western Africa; Population genetics of clonal and partially clonal organisms: theory and application to medically or veterinary relevant microbes (trypanosomes, leishmania, yeasts). Adaptive polymorphism and habitat preference evolution, the use of population genetics tools for population biology inferences in host parasite systems and the population genetics of clones are thus the main fields in which I am specially qualified.

Review:  1

13 Jul 2023
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Parasites make hosts more profitable but less available to predators

Indirect effects of parasitism include increased profitability of prey to optimal foragers

Recommended by based on reviews by Thierry DE MEEUS and Eglantine Mathieu-Bégné

Even though all living organisms are, at the same time, involved in host-parasite interactions and embedded in complex food webs, the indirect effects of parasitism are only beginning to be unveiled.

Prosnier et al. investigated the direct and indirect effects of parasitism making use of a very interesting biological system comprising the freshwater zooplankton Daphnia magna and its highly specific parasite, the iridovirus DIV-1 (Daphnia-iridescent virus 1). Daphnia are typically semitransparent, but once infected develop a white phenotype with a characteristic iridescent shine due to the enlargement of white fat cells.

In a combination of infection trials and comparison of white and non-white phenotypes collected in natural ponds, the authors demonstrated increased mortality and reduced lifetime fitness in infected Daphnia. Furthermore, white phenotypes had lower mobility, increased reflectance, larger body sizes and higher protein content than non-white phenotypes. As a consequence, total energy content was effectively doubled in white Daphnia when compared to non-white broodless Daphnia

Next the authors conducted foraging trials with Daphnia predators Notonecta (the backswimmer) and Phoxinus (the European minnow). Focusing on Notonecta, unchanged search time and increased handling time were more than compensated by the increased energy content of white Daphnia. White Daphnia were 24% more profitable and consistently preferred by Notonecta, as the optimal foraging theory would predict. The authors argue that menu decisions of optimal foragers in the field might be different, however, as the prevalence – and therefore availability - of white phenotypes in natural populations is very low.

The study therefore contributes to our understanding of the trophic context of parasitism. One shortcoming of the study is that the authors rely exclusively on phenotypic signs for determining infection. On their side, DIV-1 is currently known to be highly specific to Daphnia, their study site is well within DIV-1 distributional range, and the symptoms of infection are very conspicuous. Furthermore, the infection trial – in which non-white Daphnia were exposed to white Daphnia homogenates - effectively caused several lethal and sublethal effects associated with DIV-1 infection, including iridescence. However, the infection trial also demonstrated that part of the exposed individuals developed intermediate traits while still keeping the non-white, non-iridescent phenotype. Thus, there may be more subtleties to the association of DIV-1 infection of Daphnia with ecological and evolutionary consequences, such as costs to resistance or covert infection, that the authors acknowledge, and that would be benefitted by coupling experimental and observational studies with the determination of actual infection and viral loads.​​​

References

Prosnier L., N. Loeuille, F.D. Hulot, D. Renault, C. Piscart, B. Bicocchi, M, Deparis, M. Lam, & V. Médoc. (2023). Parasites make hosts more profitable but less available to predators. BioRxiv, ver. 4 peer-reviewed and recommended by Peer Community in Ecology. https://doi.org/10.1101/2022.02.08.479552

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DE MEEUS Thierry

  • Intertryp, IRD, Cirad, Univ Montpellier, Montpellier, France., IRD, Montpellier, France
  • Biodiversity, Dispersal & Migration, Evolutionary ecology, Habitat selection, Host-parasite interactions, Microbial ecology & microbiology, Molecular ecology, Mycology, Parasitology
  • recommender

Recommendations:  0

Review:  1

Areas of expertise
Degrees 21/01/1999: Post-PhD (Habilitation à Diriger des Recherches) at Montpellier II University. 27/06/1991: PhD of Physiology and Population and Organismal Biology at Montpellier II University. September 1989: Pre PhD of Sciences of Evolution and Ecology at Montpellier II University. September 1988: Pre-PhD of Parasitology: Ecology, Pathology at Montpellier II University. October 1987: Probation in experimental parasitology at Montpellier II University. June 1985: Masters in Population and organismal biology at P. and M. Curie University (Paris 6). Appointed positions 01/08/2015-Present: Full time senior researcher (DR1) in the IRD in the team Interactions hôtes - vecteurs - parasites dans les infections par des trypanosomatidae - (INTERTRYP), UMR177 IRD/CIRAD, , TA A-17/G, Campus International de Baillarguet, 34398 Montpellier Cedex 5, France. 01/09/2012-31/07/2015: Full time senior researcher (DR1) in the IRD in the team Interactions hôtes - vecteurs - parasites dans les infections par des trypanosomatidae - (INTERTRYP), UMR177 IRD/CIRAD and posted at the Centre International de Recherche-Développement sur l'Elevage en zone Subhumide (CIRDES), 01 BP 454, Bobo-Dioulasso 01, Burkina-Faso. 05/01/2012-01/09/2012: Full time senior researcher (DR2) in the IRD in the team Interactions hôtes - vecteurs - parasites dans les infections par des trypanosomatidae - (INTERTRYP), UMR177 IRD/CIRAD, France. 02/03/2009-04/01/2012: Full time senior researcher (DR2) in the CNRS given available to the IRD and posted at UMR 177 IRD/CIRAD, CIRDES, 01 BP 454 Bobo-Dioulasso 01, Burkina-Faso. 01/10/2005-01/03/2009: Full time senior researcher in the CNRS in the Laboratory 'Génétique et Evolution des Maladies Infectieuses', UMR 2724 CNRS/IRD Montpellier. 01/01/2004-30/09/2005: Full time and permanent researcher in the CNRS in the Laboratory 'Génétique et Evolution des Maladies Infectieuses', UMR 2724 CNRS/IRD Montpellier. 01/11/1998-31/12/2003: Full time and permanent researcher in the CNRS in the 'Centre d'Etude sur le Polymorphisme des Microorganismes', UMR 9926 CNRS/IRD Montpellier. 01/10/1993-31/10/1998: Full time and permanent researcher in the CNRS in the Laboratory 'Biologie des Populations d'Helminthes Parasites', UMR 5555 CNRS/Université Montpellier II 01/10/1992-31/09/1993: Temporary lecturer of population genetics in Montpellier II University. 01/10/1991-31/03/1992: Six month grant from the British Council at the School of Biological Sciences, University of Wales, Bangor, Gwynedd, LL57 2UW, UK. 01/10/1985-30/09/1986: Military service at Spire (Germany). Research experience During my PhD, I have studied the mechanisms of maintenance of adaptive polymorphism and evolution of habitat preference. I have used field studies, experimental tests and theoretical (analytical and computer simulations) modelling. The biological model consisted in two species of ecto-parasitic copepods and their three hosts (in the Mediterranean), turbot, brill and flounder. The fact that these organisms are marine, naturally involved me into marine biology topics. I also had to develop skills in programming (in Pascal) and in isoenzymatic genotyping. During my Post-doc in Bangor, I was trained to theoretical population genetics of structured population, in particular as regard to parameter estimation and testing of Wright's F-statistics. When coming back to Montpellier I kept studying adaptive polymorphism and habitat preference but more and more got involved in population genetic structure of hosts and their parasites. I got involved in studies on host-manipulating parasites as well. I have studied different kind of organisms as parasitic copepods, cestodes, trematodes, fungi, bacteriae, trypanosomes, leishmania, ticks, tsetse flies, gammarid amphipods, marine and fresh water snails, mussels, rats and deer. Presently my main areas of investigation concern host and parasite co-structures and the use of molecular markers in ecological inferences, and in particular in epidemiological inferences; and the theoretical and applied population genetics of clonal organisms. The main programs I am currently supervising or undertaking are: Population genetics of trypansosomes and their vectors in Western Africa; Population genetics of clonal and partially clonal organisms: theory and application to medically or veterinary relevant microbes (trypanosomes, leishmania, yeasts). Adaptive polymorphism and habitat preference evolution, the use of population genetics tools for population biology inferences in host parasite systems and the population genetics of clones are thus the main fields in which I am specially qualified.